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Retatrutide

Peptides

Triple-agonist GLP-1/GIP/glucagon receptor peptide showing superior weight loss results.

Half-life: ~6 daysDose: 1-12mg/weekNo PCT

Notes

The triple agonist mechanism may provide greater fat loss than semaglutide or tirzepatide. Start low and titrate up every 4 weeks.

Typical Dose

1-12mg/week

Frequency

Once weekly

Administration

Subcutaneous injection

Half-Life

~6 days

  • ✓Superior fat loss
  • ✓Appetite suppression
  • ✓Improved metabolic markers
  • ✓Potential muscle-sparing effects
  • ✓Energy expenditure increase
  • ⚠Nausea
  • ⚠Diarrhea
  • ⚠Decreased appetite
  • ⚠GI discomfort
TirzepatideSemaglutideL-Carnitine (Injectable)Ondansetron / ZofranMetformin